Researchers have identified a gene called CHRNA5. This gene is a major source of nicotine cause can not be forgotten by the brain. The findings open opportunities to the development of anti-smoking drug.
For information, tobacco kills 5 million people every year and a factor 1 in 10 adult deaths, with 90 percent of the deaths were linked to lung cancer.
CHRNA5 itself is a gene that controls a receptor, a driveway on the surface of brain cells, which also served to respond to the presence of nicotine molecule.
If the normal human brain, the intake of nicotine in small doses though will trigger the receptor sends a message stating "stop eating these things" in the brain.
"The dose makes the brain release a greater sense of disgust, such as the body to consume food or drink that tastes bad," said Paul Kenny, head of the team of researchers from the Scripps Research Institute, Florida, United States, as quoted from MedIndia, February 1, 2011.
When tested in mice, the effect is different if a small portion of the receptor subunits, named alpha5, removed. "The message of rejection is never sent to the brain. Finally, can not stop eating rat poison given to him, "said Kenny.
Researchers believe a similar scenario occurs in a number of human beings. From the scan further, researchers also have identified genetic changes that cause alpha5 does not work.
"About 30 to 35 percent of the population in the United States is estimated to have one of the forms of a gene that encourages CHRNA5 nicotine addiction becomes uncontrollable," said Kenny.
Kenny mentioned, the data obtained explain the reasons why individuals who have genetic variations that have a high tendency to develop a pattern of addiction to tobacco.
CHRNA5 itself is a gene that controls a receptor, a driveway on the surface of brain cells, which also served to respond to the presence of nicotine molecule.
If the normal human brain, the intake of nicotine in small doses though will trigger the receptor sends a message stating "stop eating these things" in the brain.
"The dose makes the brain release a greater sense of disgust, such as the body to consume food or drink that tastes bad," said Paul Kenny, head of the team of researchers from the Scripps Research Institute, Florida, United States, as quoted from MedIndia, February 1, 2011.
When tested in mice, the effect is different if a small portion of the receptor subunits, named alpha5, removed. "The message of rejection is never sent to the brain. Finally, can not stop eating rat poison given to him, "said Kenny.
Researchers believe a similar scenario occurs in a number of human beings. From the scan further, researchers also have identified genetic changes that cause alpha5 does not work.
"About 30 to 35 percent of the population in the United States is estimated to have one of the forms of a gene that encourages CHRNA5 nicotine addiction becomes uncontrollable," said Kenny.
Kenny mentioned, the data obtained explain the reasons why individuals who have genetic variations that have a high tendency to develop a pattern of addiction to tobacco.
Related Articles
health
- Shot of the Sun Fire Arrives on Earth
- Blood Test Can Predict Risk of Alzheimer's
- This Corn popcorn Year-Old 6700
- NASA: No evidence of Doomsday in 2012
- Showcased Genius Einstein's brain
- GMU Create Special Shoes Diabetes
- Sex Aids talisman Parasites
- Causes of Disease 'face Wolves' Found
- Chiko, Salmon Most Resistant to Climate Change
- Tigerfish, Fish Wild African Origin
news
- Alasan Windows 8 Tak Disukai
- Facebook membeli WhatsApp di Atas Rp 223 Triliun
- Shot of the Sun Fire Arrives on Earth
- African Thunderstorms from Space
- This Corn popcorn Year-Old 6700
- The Timorese Buru Tuna From 42,000 Years Ago
- Showcased Genius Einstein's brain
- Found, 'Art Studio' World's Oldest
- Sex Aids talisman Parasites
- Causes of Disease 'face Wolves' Found
technology
- Spesifikasi Lengkap BlackBerry Z3 Jakarta
- Shot of the Sun Fire Arrives on Earth
- This Corn popcorn Year-Old 6700
- The Timorese Buru Tuna From 42,000 Years Ago
- Showcased Genius Einstein's brain
- Watch out, Shark Invasion Golf Course
- Two-Headed Albino Snake Startle U.S. scientists
- Buy Tickets NASA Space Commercial Aircraft
- Found, 'Art Studio' World's Oldest
- There is a River in the Lower Amazon River
3 comment:
Terima kasih atas informasi yang hebat ini. Bagus sekali ya.. =)
Hi there, awesome site. I thought the topics you posted on were very interesting.
I tried to add your RSS to my feed reader and it a few. take a look at it, hopefully I can add you and follow.
Nicotine Addiction
We also provide the treatment services to patient which are addicted to alocohol, & drugs to know more visit at outpatient alcohol rehab san diego
Post a Comment